Twynsta tablets contains Telmisartan 40 mg and Amlodipine 5mg which are used to lower high blood pressure (hypertension). Telmisartan works by blocking the effect of angiotensin II. When the effect of angiotensin II is blocked your blood vessels relax and your blood pressure goes down. Amlodipine blocks calcium from moving into the cells of the heart and blood vessels. As a result they relax the blood vessels and increase the supply of blood and oxygen to the heart while reducing its workload.