Claritek (Clarithromycin) is a semi-synthetic macrolide antibiotic. Clarithromycin exerts its anti-bacterial action by binding to the 50s ribosomal sub-unit of susceptible bacteria and suppresses protein synthesis. It is highlypotent against a wide variety of aerobic and anaerobic gram-positive and gram-negative organisms. Indications: For treatment of infections due to susceptible organisms. Such infections include: -Lower respiratory tract infections (e.g. bronchitis pneumonia). -Upper respiratory tract infections (e.g. pharyngitis sinusitis tonsillitis). -Acute otitis media in children. -Skin and soft tissue infections (e.g. folliculitis cellulitis erysipelas impetigo abscesses). -Disseminated or localized mycobacterial infections due to MAC. -To eradicate Helicobacter pylori in treatment regimens for peptic ulcer disease. -To prevent disseminated Mycobacterium avium complex (MAC) disease in patients with advanced HIV infection. -As an alternative treatment to penicillins for prophylaxis of endocarditis.
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