Invokana contains the active substance canagliflozin which belongs to a group of medicines called “blood-glucose lowering drugs.” Invokana is used in adults to treat type 2 diabetes. This medicine works by increasing the amount of sugar removed from your body in your urine. This reduces the amount of sugar in your blood and can help prevent heart disease. Invokana can be used by itself or along with other medicines you may be using to treat your type 2 diabetes (such as metformin insulin a DPP-4 inhibitor [such as sitagliptin saxagliptin or linagliptin] a sulphonylurea [such as glimepiride or glipizide] or pioglitazone) that lower blood sugar levels. You may already be taking one or more of these to treat your type 2 diabetes. It is also important to keep following advice about diet and exercise given by your doctor or nurse.